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VPS18 抗体 (AA 298-515)

VPS18 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7175284
发货至: 中国
  • 抗原 See all VPS18 抗体
    VPS18 (Vacuolar Protein Sorting 18 Homolog (VPS18))
    抗原表位
    • 15
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 298-515
    适用
    • 35
    • 3
    • 2
    宿主
    • 32
    • 4
    克隆类型
    • 31
    • 5
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VPS18 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 11
    • 10
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Vacuolar protein sorting-associated protein 18 homolog protein (298-515AA)
    亚型
    IgG
    Top Product
    Discover our top product VPS18 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:200-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    VPS18 (Vacuolar Protein Sorting 18 Homolog (VPS18))
    别名
    VPS18 (VPS18 产品)
    别名
    MGC82750 antibody, VPS18 antibody, DDBDRAFT_0190675 antibody, DDBDRAFT_0234134 antibody, DDB_0190675 antibody, DDB_0234134 antibody, 9930024E13Rik antibody, PEP3 antibody, chunp6929 antibody, fj35h10 antibody, hm:zehl0587 antibody, wu:fj35h10 antibody, VPS18, CORVET/HOPS core subunit antibody, vacuolar protein sorting protein 18 antibody, VPS18, CORVET/HOPS core subunit S homeolog antibody, subunit of the VPS-C complex antibody, 7-fold repeat in clathrin and VPS proteins repeat-containing protein antibody, vacuolar protein sorting 18 homolog (S. cerevisiae) antibody, VPS18 CORVET/HOPS core subunit antibody, VPS18 antibody, Tc00.1047053506401.70 antibody, vps18.S antibody, vps18 antibody, Vps18 antibody
    背景

    Background: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25783203). Required for fusion of endosomes and autophagosomes with lysosomes (PubMed:25783203). Involved in dendrite development of Pukinje cells (By similarity).

    Aliases: hVPS18 antibody, PEP3 antibody, Vacuolar protein sorting 18 antibody, Vacuolar protein sorting protein 18 antibody, Vacuolar protein sorting-associated protein 18 homolog antibody, vps18 antibody, VPS18_HUMAN antibody

    UniProt
    Q9P253
    途径
    Asymmetric Protein Localization
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