UVSSA/KIAA1530 抗体 (AA 143-206) (FITC)
Quick Overview for UVSSA/KIAA1530 抗体 (AA 143-206) (FITC) (ABIN7175184)
抗原
See all UVSSA/KIAA1530 (UVSSA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 143-206
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human UV-stimulated scaffold protein A protein (143-206AA)
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亚型
- IgG
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anti-UV Stimulated Scaffold Protein A (UVSSA) (AA 1-260) antibody
UVSSA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-UV Stimulated Scaffold Protein A (UVSSA) (N-Term) antibodyUVSSA 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-UV Stimulated Scaffold Protein A (UVSSA) (AA 143-206) antibodyUVSSA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))
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别名
- UVSSA
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背景
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Background: Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to allow access to the nucleotide excision repair machinery. Not involved in processing oxidative damage.
Aliases: hypothetical protein LOC57654 antibody, K1530_HUMAN antibody, KIAA1530 antibody, Uncharacterized protein KIAA1530 antibody, UV stimulated scaffold protein A antibody, UVSS3 antibody, UVSSA antibody
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UniProt
- Q2YD98
抗原
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