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UVSSA/KIAA1530 抗体 (AA 143-206)

UVSSA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7175182
发货至: 中国
  • 抗原 See all UVSSA/KIAA1530 (UVSSA) 抗体
    UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))
    抗原表位
    • 3
    • 2
    • 1
    • 1
    AA 143-206
    适用
    宿主
    • 5
    • 2
    克隆类型
    • 6
    • 1
    多克隆
    标记
    • 4
    • 1
    • 1
    • 1
    This UVSSA/KIAA1530 antibody is un-conjugated
    应用范围
    • 4
    • 2
    • 2
    • 2
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human UV-stimulated scaffold protein A protein (143-206AA)
    亚型
    IgG
    Top Product
    Discover our top product UVSSA Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:200-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))
    别名
    UVSSA (UVSSA 产品)
    别名
    KIAA1530 antibody, UVSS3 antibody, kiaa1530 antibody, 4933407H18Rik antibody, D330017J19Rik antibody, Kiaa1530 antibody, mKIAA1530 antibody, UV stimulated scaffold protein A antibody, UVSSA antibody, uvssa antibody, Uvssa antibody
    背景

    Background: Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to allow access to the nucleotide excision repair machinery. Not involved in processing oxidative damage.

    Aliases: hypothetical protein LOC57654 antibody, K1530_HUMAN antibody, KIAA1530 antibody, Uncharacterized protein KIAA1530 antibody, UV stimulated scaffold protein A antibody, UVSS3 antibody, UVSSA antibody

    UniProt
    Q2YD98
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