Myosin VIIA 抗体 (AA 838-968) (Biotin)
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- 抗原 See all Myosin VIIA (MYO7A) 抗体
- Myosin VIIA (MYO7A)
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抗原表位
- AA 838-968
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Myosin VIIA antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Unconventional myosin-VIIa protein (838-968AA)
- 亚型
- IgG
- Top Product
- Discover our top product MYO7A Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Myosin VIIA (MYO7A)
- 别名
- MYO7A (MYO7A 产品)
- 背景
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Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
Aliases: MYO7A antibody, USH1B antibody, Unconventional myosin-VIIa antibody
- UniProt
- Q13402
- 途径
- Sensory Perception of Sound
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