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- 抗原 See all ULBP1 抗体
- ULBP1 (UL16 Binding Protein 1 (ULBP1))
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抗原表位
- AA 26-216
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ULBP1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human UL16-binding protein 1 protein (26-216AA)
- 亚型
- IgG
- Top Product
- Discover our top product ULBP1 Primary Antibody
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anti-UL16 Binding Protein 1 (ULBP1) (AA 26-216) antibody
ULBP1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3A6F11 unconjugated
anti-UL16 Binding Protein 1 (ULBP1) (AA 26-216) antibodyULBP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UL16 Binding Protein 1 (ULBP1) (AA 1-244) antibodyULBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UL16 Binding Protein 1 (ULBP1) (AA 1-234) antibodyULBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UL16 Binding Protein 1 (ULBP1) (N-Term) antibodyULBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ULBP1 (UL16 Binding Protein 1 (ULBP1))
- 别名
- ULBP1 (ULBP1 产品)
- 别名
- RAET1I antibody, A430108B07Rik antibody, MULT1 antibody, ULBP1 antibody, UL16 binding protein 1 antibody, UL16 binding protein 21 antibody, NKG2D ligand 1 antibody, ULBP1 antibody, ULBP21 antibody, Ulbp1 antibody, LOC100683099 antibody
- 背景
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Background: Ligand for the KLRK1/NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
Aliases: Alcan beta antibody, ALCAN-beta antibody, N2DL-1 antibody, N2DL1 antibody, N2DL1_HUMAN antibody, NKG2D ligand 1 antibody, NKG2D ligand 1 precursor antibody, NKG2DL1 antibody, RAET1I antibody, Retinoic acid early transcript 1I antibody, UL16 antibody, UL16 binding protein 1 antibody, UL16-binding protein 1 antibody, ULBP1 antibody
- UniProt
- Q9BZM6
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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