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ube3a 抗体 (AA 83-234)

ube3a 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7174571
发货至: 中国
  • 抗原 See all ube3a 抗体
    ube3a (Ubiquitin Protein Ligase E3A (ube3a))
    抗原表位
    • 15
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 83-234
    适用
    • 50
    • 11
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 46
    • 4
    克隆类型
    • 46
    • 4
    多克隆
    标记
    • 27
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ube3a antibody is un-conjugated
    应用范围
    • 27
    • 16
    • 15
    • 13
    • 13
    • 9
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Ubiquitin-protein ligase E3A protein (83-234AA)
    亚型
    IgG
    Top Product
    Discover our top product ube3a Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ube3a (Ubiquitin Protein Ligase E3A (ube3a))
    别名
    UBE3A (ube3a 产品)
    别名
    ANCR antibody, AS antibody, E6-AP antibody, EPVE6AP antibody, HPVE6A antibody, DDBDRAFT_0188760 antibody, DDBDRAFT_0302447 antibody, DDB_0188760 antibody, DDB_0302447 antibody, ube3a antibody, im:7140733 antibody, zgc:92173 antibody, 4732496B02 antibody, 5830462N02Rik antibody, A130086L21Rik antibody, Hpve6a antibody, mKIAA4216 antibody, As antibody, CG6190 antibody, Dmel\\CG6190 antibody, Dube3a antibody, UBE3A antibody, dUBE3A antibody, das antibody, dube3A antibody, dube3a antibody, MGC69536 antibody, UME3A antibody, ubiquitin protein ligase E3A antibody, ubiquitin-protein ligase E3A antibody, Ubiquitin protein ligase E3A antibody, ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) S homeolog antibody, ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) antibody, UBE3A antibody, ube3a antibody, LOC100194730 antibody, Ube3a antibody, ube3a.S antibody, Eint_040430 antibody
    背景

    Background: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Catalyzes the high-risk human papilloma virus E6-mediated ubiquitination of p53/TP53, contributing to the neoplastic progression of cells infected by these viruses. Additionally, may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins. Finally, UBE3A also promotes its own degradation in vivo. Plays an important role in the regulation of the circadian clock: involved in the ubiquitination of the core clock component ARNTL/BMAL1, leading to its proteasomal degradation (PubMed:24728990).

    Aliases: ANCR antibody, Angelman syndrome antibody, AS antibody, CTCL tumor antigen se37 2 antibody, CTCL tumor antigen se37-2 antibody, E6 AP antibody, E6AP antibody, E6AP ubiquitin protein ligase antibody, E6AP ubiquitin-protein ligase antibody, EPVE6AP antibody, FLJ26981 antibody, HECT-type ubiquitin transferase E3A antibody, HPVE6A antibody, Human papilloma virus E6 associated protein Angelman syndrome antibody, Human papilloma virus E6 associated protein antibody, Human papillomavirus E6-associated protein antibody, NY REN 54 antigen antibody, Oncogenic protein associated protein E6 AP antibody, Oncogenic protein associated protein E6AP antibody, Oncogenic protein-associated protein E6-AP antibody, Renal carcinoma antigen NY REN 54 antibody, Renal carcinoma antigen NY-REN-54 antibody, UBE 3A antibody, Ube3a antibody, UBE3A protein antibody, UBE3A_HUMAN antibody, Ubiquitin protein ligase E3A antibody, Ubiquitin-protein ligase E3A antibody

    UniProt
    Q05086
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway
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