UBE2W 抗体 (AA 1-151) (FITC)
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- 抗原 See all UBE2W 抗体
- UBE2W (Ubiquitin-Conjugating Enzyme E2W (UBE2W))
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抗原表位
- AA 1-151
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBE2W antibody is conjugated to FITC
- 应用范围
- 请咨询
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Ubiquitin-conjugating enzyme E2 W protein (1-151AA)
- 亚型
- IgG
- Top Product
- Discover our top product UBE2W Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- UBE2W (Ubiquitin-Conjugating Enzyme E2W (UBE2W))
- 别名
- UBE2W (UBE2W 产品)
- 别名
- UBE2W antibody, im:6905459 antibody, si:ch211-193n21.4 antibody, ube2wa antibody, UBC-16 antibody, UBC16 antibody, 6130401J04Rik antibody, ubiquitin conjugating enzyme E2 W antibody, ubiquitin-conjugating enzyme E2W (putative) antibody, ubiquitin conjugating enzyme E2 W (putative) antibody, ubiquitin conjugating enzyme E2W (putative) antibody, ubiquitin-conjugating enzyme E2W antibody, UBE2W antibody, ube2w antibody, Ube2w antibody
- 背景
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Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in degradation of misfolded chaperone substrates by mediating monoubiquitination of STUB1/CHIP, leading to recruitment of ATXN3 to monoubiquitinated STUB1/CHIP, and restriction of the length of ubiquitin chain attached to STUB1/CHIP substrates by ATXN3. After UV irradiation, but not after mitomycin-C (MMC) treatment, acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. In vitro catalyzes \'Lys-11\'-linked polyubiquitination. Transfers ubiquitin in complex with RING/U-box type E3s that do not have active site cysteine residues to form thioester bonds with ubiquitin, and preferentially ubiquitinates the N-terminus of substrates, such as ATXN3, STUB1 and SUMO2.
Aliases: FLJ11011 antibody, hUBC 16 antibody, hUBC16 antibody, Probable ubiquitin conjugating enzyme E2 W antibody, Probable ubiquitin-conjugating enzyme E2 W antibody, UBC 16 antibody, UBC-16 antibody, UBC16 antibody, UBE 2W antibody, ube2w antibody, UBE2W_HUMAN antibody, Ubiquitin carrier protein W antibody, Ubiquitin conjugating enzyme 16 antibody, Ubiquitin conjugating enzyme E2 W antibody, Ubiquitin conjugating enzyme E2W antibody, Ubiquitin protein ligase W antibody, Ubiquitin-protein ligase W antibody
- UniProt
- Q96B02
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