UBE2S 抗体 (AA 1-222)
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- 抗原 See all UBE2S 抗体
- UBE2S (Ubiquitin-Conjugating Enzyme E2S (UBE2S))
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抗原表位
- AA 1-222
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBE2S antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Ubiquitin-conjugating enzyme E2 S protein (1-222AA)
- 亚型
- IgG
- Top Product
- Discover our top product UBE2S Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- UBE2S (Ubiquitin-Conjugating Enzyme E2S (UBE2S))
- 别名
- UBE2S (UBE2S 产品)
- 别名
- E2-EPF antibody, E2EPF antibody, EPF5 antibody, 0910001J09Rik antibody, 6720465F12Rik antibody, AA409170 antibody, RGD1564746 antibody, ube2s antibody, UBE2S antibody, DDBDRAFT_0188215 antibody, DDBDRAFT_0305006 antibody, DDB_0188215 antibody, DDB_0305006 antibody, e2-epf antibody, e2epf antibody, epf5 antibody, ube2s.1 antibody, ube2s.1-b antibody, ube2s.1-a antibody, ubiquitin conjugating enzyme E2 S antibody, ubiquitin-conjugating enzyme E2S antibody, ubiquitin-conjugating enzyme e2S, putative antibody, ubiquitin-conjugating enzyme E2 S antibody, ubiquitin conjugating enzyme E2 S S homeolog antibody, ubiquitin conjugating enzyme E2 S L homeolog antibody, UBE2S antibody, Ube2s antibody, ube2s antibody, ATEG_00324 antibody, Smp_180170 antibody, MCYG_01532 antibody, ube2s.S antibody, ube2s.L antibody
- 背景
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Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes \\\'Lys-11\\\'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating \\\'Lys-11\\\'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Also acts by elongating ubiquitin chains initiated by the E2 enzyme UBE2D1/UBCH5 in vitro, it is however unclear whether UBE2D1/UBCH5 acts as a E2 enzyme for the APC/C in vivo. Also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, except \\\'Lys-48\\\'-linked polyubiquitination.
Aliases: AA409170 antibody, E2 EPF antibody, E2-EPF antibody, E2EPF antibody, EPF5 antibody, MGC101982 antibody, Ube2s antibody, UBE2S_HUMAN antibody, Ubiquitin carrier protein S antibody, Ubiquitin conjugating enzyme E2 24 kD antibody, Ubiquitin conjugating enzyme E2 24 kDa antibody, Ubiquitin conjugating enzyme E2 EPF5 antibody, Ubiquitin conjugating enzyme E2 S antibody, Ubiquitin conjugating enzyme E2S antibody, Ubiquitin protein ligase S antibody, Ubiquitin-conjugating enzyme E2 S antibody, Ubiquitin-conjugating enzyme E2-24 kDa antibody, Ubiquitin-conjugating enzyme E2-EPF5 antibody, Ubiquitin-protein ligase S antibody
- UniProt
- Q16763
- 途径
- Ubiquitin Proteasome Pathway
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