UBA52 抗体 (AA 1-128) (FITC)
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- 抗原 See all UBA52 抗体
- UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))
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抗原表位
- AA 1-128
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBA52 antibody is conjugated to FITC
- 应用范围
- 请咨询
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Ubiquitin-60S ribosomal protein L40 protein (1-128AA)
- 亚型
- IgG
- Top Product
- Discover our top product UBA52 Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))
- 别名
- UBA52 (UBA52 产品)
- 别名
- CEP52 antibody, HUBCEP52 antibody, L40 antibody, RPL40 antibody, D8Ertd21e antibody, Gm1863 antibody, Rps27a antibody, Ubb antibody, Ubc antibody, UBCEP2 antibody, UB-RPL40 antibody, MGC80109 antibody, cep52 antibody, hubcep52 antibody, rpl40 antibody, RPS27A antibody, UBB antibody, UBC antibody, wu:fa91f08 antibody, zgc:123344 antibody, UBA52 antibody, ubiquitin A-52 residue ribosomal protein fusion product 1 antibody, ubiquitin A-52 residue ribosomal protein fusion product 1 L homeolog antibody, UBA52 antibody, Uba52 antibody, uba52.L antibody, uba52 antibody
- 背景
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Background: Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair, Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation, Lys-29-linked is involved in lysosomal degradation, Lys-33-linked is involved in kinase modification, Lys-48-linked is involved in protein degradation via the proteasome, Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
Aliases: UBA52 antibody, UBCEP2 antibody, Ubiquitin-60S ribosomal protein L40 antibody, CEP52 antibody, Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin, 60S ribosomal protein L40 antibody, Large ribosomal subunit protein eL40)] antibody
- UniProt
- P62987
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation
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