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UCHL3 抗体 (C-Term)

Uchl3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7174370
发货至: 中国
  • 抗原 See all UCHL3 (Uchl3) 抗体
    UCHL3 (Uchl3) (Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3))
    抗原表位
    • 15
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    AA 1-220, C-Term
    适用
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    宿主
    • 56
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    克隆类型
    • 57
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    多克隆
    标记
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    This UCHL3 antibody is un-conjugated
    应用范围
    • 44
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    Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L3 protein (1-220AA)
    亚型
    IgG
    Top Product
    Discover our top product Uchl3 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    UCHL3 (Uchl3) (Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3))
    别名
    UCHL3 (Uchl3 产品)
    别名
    UCH-L3 antibody, UCH-6 antibody, RGD1561196 antibody, im:6908825 antibody, zgc:109963 antibody, uchl4 antibody, ubiquitin C-terminal hydrolase L3 antibody, ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) antibody, ubiquitin C-terminal hydrolase L3 L homeolog antibody, UCHL3 antibody, Uchl3 antibody, uchl3 antibody, uchl3.L antibody
    背景

    Background: Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Has a 10-fold preference for Arg and Lys at position P3\\\", and exhibits a preference towards \\\'Lys-48\\\'-linked Ubiquitin chains. Deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis. Required for stress-response retinal, skeletal muscle and germ cell maintenance. May be involved in working memory. Can hydrolyze UBB(+1), a mutated form of ubiquitin which is not effectively degraded by the proteasome and is associated with neurogenerative disorders.

    Aliases: Ubiquitin carboxyl-terminal hydrolase isozyme L3 antibody, Ubiquitin thioesterase L3 antibody, Ubiquitin thiolesterase antibody, Ubiquitin thiolesterase L3 antibody, UCH L3 antibody, UCH-L3 antibody, UCHL3 antibody, UCHL3_HUMAN antibody

    UniProt
    P15374
    途径
    Feeding Behaviour, Positive Regulation of fat Cell Differentiation
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