USP37 抗体 (AA 671-797) (FITC)
Quick Overview for USP37 抗体 (AA 671-797) (FITC) (ABIN7174326)
抗原
See all USP37 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 671-797
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Ubiquitin carboxyl-terminal hydrolase 37 protein (671-797AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- USP37 (Ubiquitin Specific Peptidase 37 (USP37))
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别名
- USP37
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背景
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Background: Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of \'Lys-11\'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of \'Lys-48\'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2) (PubMed:21596315). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1 (PubMed:27296872).
Aliases: Deubiquitinating enzyme 3 antibody, Deubiquitinating enzyme 37 antibody, EC 3.1.2.15 antibody, KIAA1594 antibody, MGC117261 antibody, OTTHUMP00000164146 antibody, tmp_locus_50 antibody, Ubiquitin carboxyl-terminal hydrolase 37 antibody, Ubiquitin specific peptidase 37 antibody, Ubiquitin specific processing protease 37 antibody, Ubiquitin specific protease 37 antibody, Ubiquitin thioesterase 37 antibody, Ubiquitin thiolesterase 37 antibody, Ubiquitin-specific-processing protease 37 antibody, UBP37_HUMAN antibody, USP37 antibody
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UniProt
- Q86T82
抗原
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