USP37 抗体 (AA 671-797)
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- 抗原 See all USP37 抗体
- USP37 (Ubiquitin Specific Peptidase 37 (USP37))
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抗原表位
- AA 671-797
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This USP37 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Ubiquitin carboxyl-terminal hydrolase 37 protein (671-797AA)
- 亚型
- IgG
- Top Product
- Discover our top product USP37 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:200-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- USP37 (Ubiquitin Specific Peptidase 37 (USP37))
- 别名
- USP37 (USP37 产品)
- 别名
- 4932415L06Rik antibody, C330008N13Rik antibody, wu:fi15b04 antibody, wu:fi38d03 antibody, zgc:152882 antibody, zgc:153999 antibody, ubiquitin specific peptidase 37 antibody, USP37 antibody, usp37 antibody, Usp37 antibody
- 背景
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Background: Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of \\\'Lys-11\\\'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of \\\'Lys-48\\\'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2) (PubMed:21596315). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1 (PubMed:27296872).
Aliases: Deubiquitinating enzyme 3 antibody, Deubiquitinating enzyme 37 antibody, EC 3.1.2.15 antibody, KIAA1594 antibody, MGC117261 antibody, OTTHUMP00000164146 antibody, tmp_locus_50 antibody, Ubiquitin carboxyl-terminal hydrolase 37 antibody, Ubiquitin specific peptidase 37 antibody, Ubiquitin specific processing protease 37 antibody, Ubiquitin specific protease 37 antibody, Ubiquitin thioesterase 37 antibody, Ubiquitin thiolesterase 37 antibody, Ubiquitin-specific-processing protease 37 antibody, UBP37_HUMAN antibody, USP37 antibody
- UniProt
- Q86T82
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