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SIRPA 抗体 (AA 31-373)

Name: SIRPA 抗体 (AA 31-373)
Brand: antibodies-online
SKU: ABIN7174125
Availability: OutOfStock

SIRPA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

Immunohistochemistry of paraffin-embedded human brain tissue using ABIN7174125 at dilution of 1:100 (SIRPA 抗体 (AA 31-373))

IHC

Immunofluorescence staining of MCF-7 cells with ABIN7174125 at 1:133, counter-stained with DAPI. (SIRPA 抗体 (AA 31-373))

2 images

产品编号 ABIN7174125

发货至: 中国

Datasheet as PDF

抗原 See all SIRPA 抗体

SIRPA (Signal-Regulatory Protein alpha (SIRPA))
抗原表位
16

14

4

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 31-373
适用
69

39

32

9

8

3

3

3
人
宿主
57

31

1

1
兔
Compatible Secondaries
克隆类型
56

34
多克隆
标记
45

10

7

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This SIRPA antibody is un-conjugated
应用范围
56

44

18

17

13

11

11

9

9

2

1

1
ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

交叉反应

人

纯化方法

>95%, Protein G purified

免疫原

Recombinant Human Tyrosine-protein phosphatase non-receptor type substrate 1 protein (31-373AA)

亚型

IgG

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anti-Signal-Regulatory Protein alpha (SIRPA) (AA 151-250) antibody
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anti-Signal-Regulatory Protein alpha (SIRPA) (AA 1-508) antibody
SIRPA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 31-370) antibody
SIRPA 适用: 人 FACS, ELISA, IP, IF 宿主: 兔 Monoclonal DM8 unconjugated

应用备注

Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

限制

仅限研究用
状态

Liquid

缓冲液

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

SIRPA (Signal-Regulatory Protein alpha (SIRPA))

别名

SIRPA (SIRPA 产品)

别名

BIT antibody, CD172A antibody, MFR antibody, MYD-1 antibody, P84 antibody, PTPNS1 antibody, SHPS1 antibody, SIRP antibody, SIRPA antibody, SIRP-A1 antibody, SIRP-B1 antibody, AI835480 antibody, Bit antibody, CD172a antibody, Ptpns1 antibody, SHP-1 antibody, SHPS-1 antibody, swc3 antibody, signal regulatory protein alpha antibody, myeloperoxidase antibody, signal-regulatory protein alpha antibody, tyrosine-protein phosphatase non-receptor type substrate 1 antibody, SIRPA antibody, MPO antibody, LOC458039 antibody, LOC100400378 antibody, LOC100590224 antibody, Sirpa antibody

背景

Background: Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function (By similarity). Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.
Aliases: Signal regulatory protein alpha type 1 antibody, Bit antibody, Brain Ig like molecule with tyrosine based activation motifs antibody, Brain Ig-like molecule with tyrosine-based activation motifs antibody, Brain immunoglobulin like molecule with tyrosine based activation motifs antibody, CD172 antigen like family member A antibody, CD172 antigen-like family member A antibody, CD172a antibody, CD172a antigen antibody, Inhibitory receptor SHPS-1 antibody, Macrophage fusion receptor antibody, MFR antibody, MYD 1 antibody, Myd 1 antigen antibody, MyD-1 antigen antibody, p84 antibody, Protein tyrosine phosphatase non receptor type substrate 1 antibody, PTPNS1 antibody, SHP substrate 1 antibody, SHPS-1 antibody, SHPS1 antibody, SHPS1_HUMAN antibody, Signal regulatory protein alpha 2 antibody, Signal regulatory protein alpha 3 antibody, Signal regulatory protein alpha antibody, Signal regulatory protein alpha type 2 antibody, Signal-regulatory protein alpha-1 antibody, Signal-regulatory protein alpha-2 antibody, Signal-regulatory protein alpha-3 antibody, SIRP antibody, Sirp-alpha-1 antibody, Sirp-alpha-2 antibody, Sirp-alpha-3 antibody, SIRPA antibody, SIRPalpha antibody, SIRPalpha1 antibody, SIRPalpha2 antibody, SIRPalpha3 antibody, Tyrosine phosphatase SHP substrate 1 antibody, Tyrosine protein phosphatase non receptor type substrate 1 antibody, Tyrosine-protein phosphatase non-receptor type substrate 1 antibody

UniProt

P78324