CSK 抗体 (AA 325-416)
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- 抗原 See all CSK 抗体
- CSK (C-Src tyrosine Kinase (CSK))
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抗原表位
- AA 325-416
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CSK antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Tyrosine-protein kinase CSK protein (325-416AA)
- 亚型
- IgG
- Top Product
- Discover our top product CSK Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CSK (C-Src tyrosine Kinase (CSK))
- 别名
- CSK (CSK 产品)
- 别名
- AW212630 antibody, C-terminal Src kinase antibody, c-src tyrosine kinase antibody, CSK, non-receptor tyrosine kinase antibody, CSK antibody, Csk antibody
- 背景
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Background: Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.
Aliases: C SRC antibody, C SRC kinase antibody, C src Tyrosine Kinase antibody, C-SRC kinase antibody, c-src tyrosine kinase antibody, Csk A antibody, CSK antibody, CSK_HUMAN antibody, CYTOPLASMIC TYROSINE KINASE antibody, EC 2.7.10.2 antibody, MGC112926 antibody, MGC117393 antibody, MGC154049 antibody, P60 Src antibody, Protein tyrosine kinase CYL antibody, Protein-tyrosine kinase CYL antibody, Proto oncogene tyrosine protein kinase antibody, Tyrosine protein kinase CSK antibody, Tyrosine-protein kinase CSK antibody, zgc:154049 antibody
- UniProt
- P41240
- 途径
- TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
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