TP53INP1 抗体 (AA 138-205)
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- 抗原 See all TP53INP1 抗体
- TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
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抗原表位
- AA 138-205
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TP53INP1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Tumor protein p53-inducible nuclear protein 1 protein (138-205AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
- 别名
- TP53INP1 (TP53INP1 产品)
- 别名
- cb1036 antibody, wu:fb70a09 antibody, wu:fi13h08 antibody, zgc:158431 antibody, TP53INP1 antibody, 2700057G22Rik antibody, SIP antibody, SIP18 antibody, SIP27 antibody, Stinp antibody, Teap antibody, TP53DINP1 antibody, TP53INP1A antibody, TP53INP1B antibody, p53DINP1 antibody, Trp53inp1 antibody, tumor protein p53 inducible nuclear protein 1 antibody, tumor protein p53 inducible nuclear protein 1 S homeolog antibody, transformation related protein 53 inducible nuclear protein 1 antibody, TP53INP1 antibody, tp53inp1.S antibody, tp53inp1 antibody, Trp53inp1 antibody, Tp53inp1 antibody
- 背景
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Background: Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on \'Ser-46\' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.
Aliases: DKFZp434M1317 antibody, FLJ22139 antibody, p53 damage inducible nuclear protein 1 antibody, p53 dependent damage inducible nuclear protein 1 antibody, p53 inducible nuclear protein 1 antibody, p53 inducible p53DINP1 antibody, p53-dependent damage-inducible nuclear protein 1 antibody, p53DINP1 antibody, SIP antibody, Stress induced protein antibody, Stress-induced protein antibody, T53I1_HUMAN antibody, Teap antibody, TP53 DINP1 antibody, TP53 INP1 antibody, TP53DINP1 antibody, TP53INP1 antibody, TP53INP1A antibody, TP53INP1B antibody, Tumor protein p53 inducible nuclear protein 1 antibody, Tumor protein p53-inducible nuclear protein 1 antibody
- UniProt
- Q96A56
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