Tuberin 抗体 (AA 1396-1496)
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- 抗原 See all Tuberin (TSC2) 抗体
- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
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抗原表位
- AA 1396-1496
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Tuberin antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Tuberin protein (1396-1496AA)
- 亚型
- IgG
- Top Product
- Discover our top product TSC2 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
- 别名
- TSC2 (TSC2 产品)
- 别名
- TSC2 antibody, fc16b02 antibody, tuberin antibody, wu:fc16b02 antibody, LAM antibody, TSC4 antibody, Nafld antibody, Tcs2 antibody, Rc antibody, TSC complex subunit 2 antibody, tuberin antibody, hypothetical protein antibody, tuberous sclerosis 2 antibody, TSC2 antibody, LOC5569538 antibody, tsc2 antibody, PGTG_00159 antibody, Tsc2 antibody
- 背景
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Background: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. May also play a role in microtubule-mediated protein transport. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5.
Aliases: FLJ43106 antibody, LAM antibody, OTTHUMP00000158940 antibody, OTTHUMP00000198394 antibody, OTTHUMP00000198395 antibody, PPP1R160 antibody, Protein phosphatase 1, regulatory subunit 160 antibody, TSC complex subunit 2 antibody, tsc2 antibody, TSC2_HUMAN antibody, TSC4 antibody, TSC4 gene, formerly antibody, TSC4, formerly antibody, Tuberin antibody, Tuberous sclerosis 2 antibody, Tuberous sclerosis 2 protein antibody, Tuberous sclerosis 2 protein homolog antibody
- UniProt
- P49815
- 途径
- RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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