TGS1 抗体 (AA 714-853)
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- 抗原 See all TGS1 抗体
- TGS1 (Trimethylguanosine Synthase 1 (TGS1))
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抗原表位
- AA 714-853
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TGS1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Trimethylguanosine synthase protein (714-853AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TGS1 (Trimethylguanosine Synthase 1 (TGS1))
- 别名
- TGS1 (TGS1 产品)
- 别名
- NCOA6IP antibody, PIMT antibody, PIPMT antibody, D4Ertd800e antibody, Ncoa6ip antibody, Pimt antibody, trimethylguanosine synthase 1 antibody, trimethylguanosine synthase 1 L homeolog antibody, TGS1 antibody, Tgs1 antibody, tgs1.L antibody
- 背景
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Background: Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.
Aliases: Cap specific guanine N2 methyltransferase antibody, Cap-specific guanine-N2 methyltransferase antibody, CLL associated antigen KW 2 antibody, CLL-associated antigen KW-2 antibody, DKFZp762A163 antibody, FLJ22995 antibody, HCA137 antibody, Hepatocellular carcinoma associated antigen 137 antibody, Hepatocellular carcinoma-associated antigen 137 antibody, NCOA6IP antibody, Nuclear receptor coactivator 6 interacting protein antibody, Nuclear receptor coactivator 6-interacting protein antibody, PIMT antibody, PIPMT antibody, PRIP interacting protein PIPMT antibody, PRIP interacting protein with methyltransferase domain antibody, PRIP interacting protein with methyltransferase motif antibody, PRIP-interacting protein with methyltransferase motif antibody, SEREX defined antibody, TGS 1 antibody, Tgs1 antibody, TGS1_HUMAN antibody, Trimethylguanosine synthase antibody, Trimethylguanosine synthase homolog (S. cerevisiae) antibody, Trimethylguanosine synthase homolog antibody
- UniProt
- Q96RS0
- 途径
- Mitotic G1-G1/S Phases, Regulation of Lipid Metabolism by PPARalpha, Ribonucleoprotein Complex Subunit Organization
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