TCHP 抗体 (AA 1-498)
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- 抗原 See all TCHP 抗体
- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
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抗原表位
- AA 1-498
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TCHP antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Trichoplein keratin filament-binding protein (1-498AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
- 别名
- TCHP (TCHP 产品)
- 别名
- TpMs antibody, A930031F18Rik antibody, AV279199 antibody, RGD1310813 antibody, zgc:136634 antibody, trichoplein keratin filament binding antibody, trichoplein, keratin filament binding antibody, trichoplein, keratin filament binding L homeolog antibody, TCHP antibody, tchp antibody, Tchp antibody, tchp.L antibody
- 背景
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Background: Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a \'capping\' or \'branching\' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis (PubMed:25270598).
Aliases: TCHP antibody, Trichoplein keratin filament-binding protein antibody, Protein TCHP antibody, Mitochondrial protein with oncostatic activity antibody, Mitostatin antibody, Tumor suppressor protein antibody
- UniProt
- Q9BT92
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