TRIB3 抗体 (AA 152-325)
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- 抗原 See all TRIB3 抗体
- TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
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抗原表位
- AA 152-325
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRIB3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Tribbles homolog 3 protein (152-325AA)
- 亚型
- IgG
- Top Product
- Discover our top product TRIB3 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
- 别名
- TRIB3 (TRIB3 产品)
- 别名
- zgc:76966 antibody, TRIB3 antibody, C20orf97 antibody, NIPK antibody, SINK antibody, SKIP3 antibody, TRB3 antibody, Ifld2 antibody, Nipk antibody, TRB-3 antibody, Trb3 antibody, tribbles pseudokinase 3 antibody, trib3 antibody, TRIB3 antibody, Trib3 antibody
- 背景
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Background: Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the \\\'Thr-308\\\' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.
Aliases: C20orf97 antibody, Neuronal cell death inducible putative kinase antibody, Neuronal cell death-inducible putative kinase antibody, NIPK antibody, p65 interacting inhibitor of NF-kappaB antibody, p65-interacting inhibitor of NF-kappa-B antibody, SINK antibody, SKIP 3 antibody, SKIP3 antibody, TRB 3 antibody, TRB-3 antibody, TRB3 antibody, TRIB 3 antibody, Trib3 antibody, TRIB3_HUMAN antibody, Tribbles homolog 3 antibody, Tribbles pseudokinase 3 antibody, Tribbles3 antibody
- UniProt
- Q96RU7
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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