MIA3 抗体 (AA 1447-1626)
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- 抗原 See all MIA3 抗体
- MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))
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抗原表位
- AA 1447-1626
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MIA3 antibody is un-conjugated
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Transport and Golgi organization protein 1 homolog protein (1447-1626AA)
- 亚型
- IgG
- Top Product
- Discover our top product MIA3 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))
- 别名
- MIA3 (MIA3 产品)
- 别名
- CG11098 antibody, Dmel\\CG11098 antibody, TANGO1 antibody, MIA3 antibody, 9130229H14Rik antibody, A930039G15Rik antibody, AU022327 antibody, B230399H06Rik antibody, C80126 antibody, Gm1525 antibody, Tango antibody, ARNT antibody, D320 antibody, TANGO antibody, UNQ6077 antibody, Transport and Golgi organization 1 antibody, MIA family member 3, ER export factor antibody, melanoma inhibitory activity family, member 3 antibody, melanoma inhibitory activity protein 3 antibody, melanoma inhibitory activity family member 3 antibody, melanoma inhibitory activity 3 antibody, Tango1 antibody, MIA3 antibody, LOC100055507 antibody, mia3 antibody, Mia3 antibody
- 背景
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Background: Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum (PubMed:27138255, PubMed:19269366). Required for correct assembly of COPII coat components at endoplasmic reticulum exit sites (ERES) and for the localization of SEC16A and membrane-bound ER-resident complexes consisting of CTAGE5 and PREB/SEC12 to ERES (PubMed:28442536).
Aliases: ARNT antibody, C219 reactive peptide antibody, C219-reactive peptide antibody, D320 antibody, Melanoma inhibitory activity family, member 3 antibody, Melanoma inhibitory activity protein 3 antibody, Mia3 antibody, MIA3_HUMAN antibody, RP11-378J18.4 antibody, TANGO antibody, Transport and Golgi organization protein 1 antibody, UNQ6077 antibody
- UniProt
- Q5JRA6
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