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TMED2 抗体 (AA 26-111)

TMED2 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7172975
发货至: 中国
  • 抗原 See all TMED2 抗体
    TMED2 (Transmembrane Emp24 Domain Trafficking Protein 2 (TMED2))
    抗原表位
    • 8
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-111
    适用
    • 37
    • 16
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 37
    克隆类型
    • 37
    多克隆
    标记
    • 16
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TMED2 antibody is un-conjugated
    应用范围
    • 25
    • 19
    • 17
    • 4
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Transmembrane emp24 domain-containing protein 2 protein (26-111AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    TMED2 (Transmembrane Emp24 Domain Trafficking Protein 2 (TMED2))
    别名
    TMED2 (TMED2 产品)
    别名
    P24A antibody, RNP24 antibody, p24 antibody, 1110032D12Rik antibody, 1810020N21Rik antibody, Rnp24 antibody, Sid394 antibody, p24beta1 antibody, Chop24 antibody, transmembrane p24 trafficking protein 2 antibody, TMED2 antibody, Tmed2 antibody
    背景

    Background: Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor, the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1. In COPI vesicle-mediated retrograde transport inhibits the GTPase-activating activity of ARFGAP1 towards ARF1 thus preventing immature uncoating and allowing cargo selection to take place. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2RL1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Facilitates CASR maturation and stabilization in the early secretory pathway and increases CASR plasma membrane targeting. Proposed to be involved in organization of intracellular membranes such as the maintenance of the Golgi apparatus. May also play a role in the biosynthesis of secreted cargo such as eventual processing.

    Aliases: coated vesicle membrane protein antibody, Membrane protein p24A antibody, p24 antibody, p24 family protein beta-1 antibody, P24A antibody, p24beta1 antibody, RNP24 antibody, Sid 394 antibody, Sid394 antibody, TMED2 antibody, TMED2_HUMAN antibody, transmembrane emp24 domain trafficking protein 2 antibody, Transmembrane emp24 domain-containing protein 2 antibody

    UniProt
    Q15363
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