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LRRC32 抗体 (AA 301-500)

LRRC32 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7172807
发货至: 中国
  • 抗原 See all LRRC32 抗体
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    抗原表位
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-500
    适用
    • 26
    • 10
    • 9
    • 1
    宿主
    • 19
    • 13
    • 1
    • 1
    克隆类型
    • 20
    • 14
    多克隆
    标记
    • 18
    • 7
    • 4
    • 2
    • 2
    • 1
    This LRRC32 antibody is un-conjugated
    应用范围
    • 17
    • 16
    • 13
    • 5
    • 4
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Transforming growth factor beta activator LRRC32 protein (301-500AA)
    亚型
    IgG
    Top Product
    Discover our top product LRRC32 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    别名
    LRRC32 (LRRC32 产品)
    别名
    D11S833E antibody, GARP antibody, AI426318 antibody, D11S833Eh antibody, D7H11S833E antibody, EG434215 antibody, Garp antibody, leucine rich repeat containing 32 antibody, LRRC32 antibody, Lrrc32 antibody
    背景

    Background: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19750484, PubMed:19651619, PubMed:22278742). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:22278742). Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta (PubMed:22278742). Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs) (PubMed:19750484, PubMed:19651619). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3) (By similarity).

    Aliases: D11S833E antibody, GARP antibody, Garpin antibody, Glycoprotein A repetitions predominant antibody, Leucine rich repeat containing 32 antibody, Leucine-rich repeat-containing protein 32 antibody, LRC32_HUMAN antibody, LRRC32 antibody

    UniProt
    Q14392
    途径
    Activated T Cell Proliferation
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