TEAD4 抗体 (AA 74-434)
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- 抗原 See all TEAD4 抗体
- TEAD4 (TEA Domain Family Member 4 (TEAD4))
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抗原表位
- AA 74-434
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TEAD4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Transcriptional enhancer factor TEF-3 protein (74-434AA)
- 亚型
- IgG
- Top Product
- Discover our top product TEAD4 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TEAD4 (TEA Domain Family Member 4 (TEAD4))
- 别名
- TEAD4 (TEAD4 产品)
- 别名
- TEAD4 antibody, rtef1 antibody, tef-3 antibody, eftr-2 antibody, tefr-1 antibody, tcf13l1 antibody, hrtef-1b antibody, xdtef-1 antibody, xlDTEF-1 antibody, RTEF-1 antibody, TEF-1 antibody, TEF-3 antibody, EFTR-2 antibody, RTEF1 antibody, TCF13L1 antibody, TEF3 antibody, TEFR-1 antibody, hRTEF-1B antibody, ETFR-2 antibody, Etfr2 antibody, FR-19 antibody, TEAD-4 antibody, Tcf13r1 antibody, Tef3 antibody, Tefr antibody, Tefr1 antibody, Tefr1a antibody, TEA domain transcription factor 4 antibody, TEA domain transcription factor 4 S homeolog antibody, TEA domain family member 4 antibody, TEAD4 antibody, tead4 antibody, tead4.S antibody, Tead4 antibody
- 背景
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Background: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC \\\'enhansons\\\' (5\\\'-GTGGAATGT-3\\\') and activates transcription. Binds to the M-CAT motif.
Aliases: EFTR 2 antibody, EFTR2 antibody, hRTEF 1B antibody, hRTEF1B antibody, MGC9014 antibody, OTTHUMP00000238119 antibody, OTTHUMP00000238122 antibody, OTTHUMP00000238124 antibody, Related to TEF 1 antibody, Related to TEF1 antibody, Related transcription enhancer factor 1B antibody, RTEF1 antibody, TCF13L1 antibody, TEA domain family member 4 antibody, TEAD 4 antibody, TEAD-4 antibody, TEAD4 antibody, TEAD4_HUMAN antibody, TEF 3 antibody, TEF3 antibody, TEFR 1 antibody, TEFR1 antibody, Transcription factor 13 (SV40 transcriptional enhancer factor) like 1 antibody, Transcription factor 13 like 1 antibody, Transcription factor 13-like 1 antibody, Transcription factor RTEF 1 antibody, Transcription factor RTEF-1 antibody, Transcription factor RTEF1 antibody, Transcriptional enhancer factor 1 related antibody, Transcriptional enhancer factor 3 antibody, Transcriptional enhancer factor TEF 3 antibody, Transcriptional enhancer factor TEF-3 antibody, Transcriptional enhancer factor TEF3 antibody
- UniProt
- Q15561
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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