RFX3 抗体 (AA 201-413) (Biotin)
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- 抗原 See all RFX3 抗体
- RFX3 (Regulatory Factor X 3 (RFX3))
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抗原表位
- AA 201-413
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RFX3 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Transcription factor RFX3 protein (201-413AA)
- 亚型
- IgG
- Top Product
- Discover our top product RFX3 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RFX3 (Regulatory Factor X 3 (RFX3))
- 别名
- RFX3 (RFX3 产品)
- 别名
- ba32f11.1 antibody, C230093O12Rik antibody, MRFX3 antibody, zgc:153245 antibody, regulatory factor X3 antibody, regulatory factor X, 3 (influences HLA class II expression) antibody, Rfx3 antibody, rfx3 antibody, RFX3 antibody
- 背景
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Background: Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocilia and left-right asymmetry specification during embryogenesis. Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation. Regulates the expression of genes involved in ciliary assembly (DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility (DNAH11, DNAH9 and DNAH5). Together with RFX6, participates in the differentiation of 4 of the 5 islet cell types during endocrine pancreas development, with the exception of pancreatic PP (polypeptide-producing) cells. Regulates transcription by forming a heterodimer with another RFX protein and binding to the X-box in the promoter of target genes. Acts as a transcription factor. Represses transcription of MAP1A in non-neuronal cells but not in neuronal cells.
Aliases: bA32F11.1 antibody, DNA binding protein RFX3 antibody, Regulatory factor X 3 antibody, Regulatory factor X, 3 (influences HLA class II expression) antibody, RFX3 antibody, RFX3_HUMAN antibody, Transcription factor RFX3 antibody
- UniProt
- P48380
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