MAFB 抗体 (AA 168-323)
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- 抗原 See all MAFB 抗体
- MAFB (Transcription Factor MafB (MAFB))
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抗原表位
- AA 168-323
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAFB antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Transcription factor MafB protein (168-323AA)
- 亚型
- IgG
- Top Product
- Discover our top product MAFB Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:5000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- MAFB (Transcription Factor MafB (MAFB))
- 别名
- MAFB (MAFB 产品)
- 别名
- MAFB antibody, krml antibody, Maf-B antibody, XMafB antibody, kreisler antibody, MGC108453 antibody, valentino antibody, KRML antibody, MCTO antibody, Krml antibody, b-maf antibody, kr antibody, mafb antibody, val antibody, wu:fc22d11 antibody, wu:fj82a09 antibody, Kreisler antibody, Krml1 antibody, MAF bZIP transcription factor B antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B S homeolog antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba antibody, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) antibody, MAFB antibody, mafb antibody, mafb.S antibody, Mafb antibody, mafba antibody
- 背景
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Background: Acts as a transcriptional activator or repressor (PubMed:27181683). Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Aliases: Kreisler antibody, Kreisler (mouse) maf related leucine zipper homolog antibody, Kreisler maf related leucine zipper homolog antibody, KRML antibody, MAF bZIP transcription factor B antibody, Maf-B antibody, Mafb antibody, MAFB/Kreisler basic region/leucine zipper transcription factor antibody, MAFB_HUMAN antibody, MGC43127 antibody, Segmentation protein KR antibody, Transcription factor MafB antibody, V maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) antibody, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B antibody
- UniProt
- Q9Y5Q3
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