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MAF 抗体 (AA 55-180)

MAF 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7172574
发货至: 中国
  • 抗原 See all MAF 抗体
    MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
    抗原表位
    • 15
    • 14
    • 10
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 55-180
    适用
    • 53
    • 50
    • 18
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 66
    • 3
    克隆类型
    • 65
    • 4
    多克隆
    标记
    • 34
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAF antibody is un-conjugated
    应用范围
    • 43
    • 29
    • 13
    • 13
    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Transcription factor Maf protein (55-180AA)
    亚型
    IgG
    Top Product
    Discover our top product MAF Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
    别名
    MAF (MAF 产品)
    别名
    MAF antibody, DKFZp459D1731 antibody, 2810401A20Rik antibody, A230108G15Rik antibody, AW047063 antibody, c-maf antibody, CCA4 antibody, c-MAF antibody, Maf2 antibody, cMaf antibody, Z-cmaf antibody, c-Maf antibody, fl13d12 antibody, wu:fl13d12 antibody, C-Maf antibody, MAF bZIP transcription factor antibody, v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) antibody, avian musculoaponeurotic fibrosarcoma oncogene homolog antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a) antibody, MAF antibody, Maf antibody, mafa antibody
    背景

    Background: Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element. Activates transcription of the CD13 proximal promoter in endothelial cells. Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction. Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. Binds to the sequence 5\'-[GT]G[GC]N[GT]NCTCAGNN-3\' in the L7 promoter. Binds to the T-MARE (Maf response element) sites of lens-specific alpha- and beta-crystallin gene promoters. Binds element G1 on the glucagon promoter. Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells (By similarity). When overexpressed, represses anti-oxidant response element (ARE)-mediated transcription. Involved either as an oncogene or as a tumor suppressor, depending on the cell context. Binds to the ARE sites of detoxifying enzyme gene promoters.

    Aliases: AS42 oncogene homolog antibody, Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene antibody, Avian musculoaponeurotic fibrosarcoma (v maf) antibody, c maf proto oncogene antibody, cMaf antibody, maf antibody, MAF_HUMAN antibody, MAF2 antibody, MGC71685 antibody, Proto oncogene c Maf antibody, Proto-oncogene c-maf antibody, Transcription factor Maf antibody, v maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) antibody, v maf musculoaponeurotic fibrosarcoma oncogene homolog antibody, V-maf musculoaponeurotic fibrosarcoma oncogene homolog antibody

    UniProt
    O75444
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