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TRIAP1 抗体 (AA 1-76)

TRIAP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7172318
发货至: 中国
  • 抗原 See all TRIAP1 抗体
    TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))
    抗原表位
    AA 1-76
    适用
    • 2
    • 1
    • 1
    宿主
    • 2
    克隆类型
    • 2
    多克隆
    标记
    • 2
    This TRIAP1 antibody is un-conjugated
    应用范围
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human TP53-regulated inhibitor of apoptosis 1 protein (1-76AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))
    别名
    TRIAP1 (TRIAP1 产品)
    别名
    MDM35 antibody, P53CSV antibody, WF-1 antibody, 1810015M01Rik antibody, AU020874 antibody, AU043831 antibody, P53csv antibody, Wf-1 antibody, p53csv-A antibody, triap1 antibody, triap1a antibody, p53csv-B antibody, triap1-a antibody, triap1-b antibody, triap1b antibody, zgc:112025 antibody, TP53 regulated inhibitor of apoptosis 1 antibody, TP53 regulated inhibitor of apoptosis 1 S homeolog antibody, TP53 regulated inhibitor of apoptosis 1 L homeolog antibody, TRIAP1 antibody, Triap1 antibody, triap1.S antibody, triap1.L antibody, triap1 antibody
    背景

    Background: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane (PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo) (PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis (PubMed:15735003).

    Aliases: p53-inducible cell-survival factor antibody, p53CSV antibody, Protein 15E1.1 antibody, TP53-regulated inhibitor of apoptosis 1 antibody, TRIA1_HUMAN antibody, Triap1 antibody, WF 1 antibody, WF1 antibody

    UniProt
    O43715
    途径
    Negative Regulation of intrinsic apoptotic Signaling
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