TXNIP 抗体 (AA 299-381)
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- 抗原 See all TXNIP 抗体
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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抗原表位
- AA 299-381
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TXNIP antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Thioredoxin-interacting protein (299-381AA)
- 亚型
- IgG
- Top Product
- Discover our top product TXNIP Primary Antibody
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- 应用备注
- Recommended dilution: IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
- 别名
- TXNIP (TXNIP 产品)
- 别名
- EST01027 antibody, HHCPA78 antibody, THIF antibody, VDUP1 antibody, Gm348 antibody, Trf3 antibody, TBP2 antibody, TRF3 antibody, 1200008J08Rik antibody, AA682105 antibody, Hyplip1 antibody, Tbp-2 antibody, Vdup1 antibody, sb:cb368 antibody, txnip antibody, thioredoxin interacting protein antibody, TATA box binding protein like 2 antibody, TATA-box binding protein like 2 antibody, thioredoxin interacting protein L homeolog antibody, thioredoxin interacting protein a antibody, TXNIP antibody, Tbpl2 antibody, TBPL2 antibody, Txnip antibody, txnip.L antibody, txnip antibody, txnipa antibody
- 背景
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Background: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
Aliases: EST01027 antibody, HHCPA78 antibody, THIF antibody, Thioredoxin binding protein 2 antibody, Thioredoxin interacting protein antibody, Thioredoxin-binding protein 2 antibody, Thioredoxin-interacting protein antibody, TXNIP antibody, TXNIP_HUMAN antibody, Upregulated by 1,25 dihydroxyvitamin D 3 antibody, VDUP1 antibody, Vitamin D3 up-regulated protein 1 antibody
- UniProt
- Q9H3M7
- 途径
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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