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TXNIP 抗体 (AA 299-381)

TXNIP 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7172027
发货至: 中国
  • 抗原 See all TXNIP 抗体
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    抗原表位
    • 16
    • 14
    • 9
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 299-381
    适用
    • 67
    • 48
    • 33
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 76
    • 5
    克隆类型
    • 68
    • 13
    多克隆
    标记
    • 30
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TXNIP antibody is un-conjugated
    应用范围
    • 58
    • 31
    • 15
    • 14
    • 14
    • 8
    • 8
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Thioredoxin-interacting protein (299-381AA)
    亚型
    IgG
    Top Product
    Discover our top product TXNIP Primary Antibody
  • 应用备注
    Recommended dilution: IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    别名
    TXNIP (TXNIP 产品)
    别名
    EST01027 antibody, HHCPA78 antibody, THIF antibody, VDUP1 antibody, Gm348 antibody, Trf3 antibody, TBP2 antibody, TRF3 antibody, 1200008J08Rik antibody, AA682105 antibody, Hyplip1 antibody, Tbp-2 antibody, Vdup1 antibody, sb:cb368 antibody, txnip antibody, thioredoxin interacting protein antibody, TATA box binding protein like 2 antibody, TATA-box binding protein like 2 antibody, thioredoxin interacting protein L homeolog antibody, thioredoxin interacting protein a antibody, TXNIP antibody, Tbpl2 antibody, TBPL2 antibody, Txnip antibody, txnip.L antibody, txnip antibody, txnipa antibody
    背景

    Background: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).

    Aliases: EST01027 antibody, HHCPA78 antibody, THIF antibody, Thioredoxin binding protein 2 antibody, Thioredoxin interacting protein antibody, Thioredoxin-binding protein 2 antibody, Thioredoxin-interacting protein antibody, TXNIP antibody, TXNIP_HUMAN antibody, Upregulated by 1,25 dihydroxyvitamin D 3 antibody, VDUP1 antibody, Vitamin D3 up-regulated protein 1 antibody

    UniProt
    Q9H3M7
    途径
    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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