TNKS2 抗体 (AA 1-246)
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- 抗原 See all TNKS2 抗体
- TNKS2 (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2))
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抗原表位
- AA 1-246
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNKS2 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Tankyrase-2 protein (1-246AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TNKS2 (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2))
- 别名
- TNKS2 (TNKS2 产品)
- 别名
- ARTD6 antibody, PARP-5b antibody, PARP-5c antibody, PARP5B antibody, PARP5C antibody, TANK2 antibody, TNKL antibody, pART6 antibody, 5430432P15Rik antibody, AA517131 antibody, AI662480 antibody, TNKS-2 antibody, Tank2 antibody, tankyrase-2 antibody, TNKS2 antibody, tankyrase-1 antibody, tnks antibody, tnks.L antibody, tnks2 antibody, tankyrase 2 antibody, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 antibody, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase S homeolog antibody, TNKS2 antibody, Tnks2 antibody, tnks2 antibody, tnks.S antibody
- 背景
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Background: Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Stimulates 26S proteasome activity.
Aliases: ADP-ribosyltransferase diphtheria toxin-like 6 antibody, ARTD6 antibody, PARP 5b antibody, PARP 5c antibody, PARP-5b antibody, PARP-5c antibody, PARP5B antibody, PARP5C antibody, pART6 antibody, Poly [ADP ribose] polymerase 5B antibody, Poly [ADP-ribose] polymerase 5B antibody, TANK2 antibody, Tankyrase 2 antibody, Tankyrase II antibody, Tankyrase like protein antibody, Tankyrase related protein antibody, Tankyrase TRF1 interacting ankyrin related ADP ribose polymerase 2 antibody, Tankyrase-2 antibody, Tankyrase-like protein antibody, Tankyrase-related protein antibody, TNKL antibody, TNKS 2 antibody, TNKS-2 antibody, TNKS2 antibody, TNKS2_HUMAN antibody, TRF1 Interacting Ankyrin Related ADP ribose polymerase 2 antibody, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 antibody
- UniProt
- Q9H2K2
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