TNKS 抗体 (AA 35-130) (HRP)
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- 抗原 See all TNKS 抗体
- TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))
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抗原表位
- AA 35-130
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNKS antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Tankyrase-1 protein (35-130AA)
- 亚型
- IgG
- Top Product
- Discover our top product TNKS Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))
- 别名
- TNKS (TNKS 产品)
- 别名
- wu:fe02c12 antibody, ARTD5 antibody, PARP-5a antibody, PARP5A antibody, PARPL antibody, TIN1 antibody, TINF1 antibody, TNKS1 antibody, pART5 antibody, 4930554K12Rik antibody, AI662855 antibody, C86528 antibody, D130072O21Rik antibody, TANK1 antibody, mTNKS1 antibody, tankyrase-1 antibody, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b antibody, tankyrase antibody, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase antibody, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 S homeolog antibody, tnksb antibody, TNKS antibody, Tnks antibody, tnks2.S antibody
- 背景
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Background: Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates PARsylation of TERF1, thereby contributing to the regulation of telomere length. Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. May be involved in spindle pole assembly through PARsylation of NUMA1. Stimulates 26S proteasome activity.
Aliases: ADP-ribosyltransferase diphtheria toxin-like 5 antibody, OTTHUMP00000115550 antibody, OTTHUMP00000224675 antibody, PARP 5a antibody, PARP5A antibody, PARPL antibody, pART5 antibody, Poly [ADP-ribose] polymerase 5A antibody, TANK 1 antibody, TANK1 antibody, Tankyrase 1 antibody, Tankyrase I antibody, Tankyrase TRF1 interacting ankyrin related ADP ribose polymerase antibody, Tankyrase-1 antibody, Tankyrase1 antibody, TankyraseI antibody, TIN 1 antibody, TIN1 antibody, TINF 1 antibody, TINF1 antibody, TNKS 1 antibody, TNKS antibody, TNKS-1 antibody, TNKS1 antibody, TNKS1_HUMAN antibody, TRF1 interacting ankyrin related ADP ribose polymerase antibody, TRF1-interacting ankyrin-related ADP-ribose polymerase antibody
- UniProt
- O95271
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