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CD3 epsilon 抗体 (AA 23-207)

Name: CD3 epsilon 抗体 (AA 23-207)
Brand: antibodies-online
SKU: ABIN7171386
Availability: OutOfStock

CD3E 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

Western blot All lanes: CD3E antibody at 1. (CD3 epsilon 抗体 (AA 23-207))

IHC image of ABIN7171386 diluted at 1:80 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. (CD3 epsilon 抗体 (AA 23-207))

IHC

Immunofluorescence staining of PC-3 cells with ABIN7171386 at 1:53, counter-stained with DAPI. (CD3 epsilon 抗体 (AA 23-207))

IHC image of ABIN7171386 diluted at 1:80 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. (CD3 epsilon 抗体 (AA 23-207))

IHC

4 images

产品编号 ABIN7171386

发货至: 中国

Datasheet as PDF

抗原 See all CD3 epsilon (CD3E) 抗体

CD3 epsilon (CD3E)
抗原表位
24

20

16

16

13

12

8

8

6

4

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 23-207
适用
215

154

51

42

18

8

8

8

7

4

4

4

4

3

3

3

3

3

3

1

1
人
宿主
132

112

33

23

20

8

1

1

1
兔
Compatible Secondaries
克隆类型
211

114

6
多克隆
标记
121

31

28

20

15

8

8

6

5

4

4

4

4

4

4

4

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This CD3 epsilon antibody is un-conjugated
应用范围
237

134

94

79

70

69

27

27

24

22

14

13

13

12

8

6

4

3

3

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

交叉反应

人

纯化方法

>95%, Protein G purified

免疫原

Recombinant Human T-cell surface glycoprotein CD3 epsilon chain protein (23-207AA)

亚型

IgG

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anti-CD3 epsilon (CD3E) (AA 23-207) antibody
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CD3E 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

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anti-CD3 epsilon (CD3E) (AA 23-119) antibody
CD3E 适用: 人 FACS, WB, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal C3e-1931 unconjugated

anti-CD3 epsilon (CD3E) (AA 156-168), (Cytoplasmic Domain) antibody
CD3E 适用: 人, 大鼠, Pig, 兔, Cow, 马, 豚鼠, 小鸡 FACS, WB, IF 宿主: 小鼠 Monoclonal PC3-188A unconjugated

anti-CD3 epsilon (CD3E) (C-Term) antibody
CD3E 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (C-Term) antibody
CD3E 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (AA 25-207) antibody
CD3E 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (AA 28-185) antibody
CD3E 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD3 epsilon (CD3E) antibody
CD3E 适用: 人 WB, IHC, IF 宿主: 兔 Chimeric YTH 12-5 unconjugated Recombinant Antibody

应用备注

Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

限制

仅限研究用
状态

Liquid

缓冲液

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

CD3 epsilon (CD3E)

别名

CD3E (CD3E 产品)

别名

cd3e antibody, CD3E antibody, t3e antibody, tcre antibody, AI504783 antibody, CD3 antibody, CD3epsilon antibody, T3e antibody, T3E antibody, TCRE antibody, CD3e molecule antibody, CD3 antigen, epsilon polypeptide antibody, cd3e antibody, CD3E antibody, Cd3e antibody

背景

Background: Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways (PubMed:2470098). In addition of this role of signal transduction in T-cell activation, CD3E plays an essential role in correct T-cell development. Initiates the TCR-CD3 complex assembly by forming the two heterodimers CD3D/CD3E and CD3G/CD3E. Participates also in internalization and cell surface down-regulation of TCR-CD3 complexes via endocytosis sequences present in CD3E cytosolic region (PubMed:10384095, PubMed:26507128).
Aliases: CD3 epsilon antibody, CD3e antibody, CD3e antigen antibody, CD3e antigen epsilon polypeptide (TiT3 complex) antibody, CD3E antigen epsilon polypeptide antibody, CD3E antigen, epsilon subunit antibody, CD3e molecule epsilon antibody, CD3e molecule, epsilon (CD3 TCR complex) antibody, CD3e molecule, epsilon (CD3-TCR complex) antibody, CD3E_HUMAN antibody, IMD18 antibody, T cell antigen receptor complex epsilon subunit of T3 antibody, T cell surface antigen T3/Leu 4 epsilon chain antibody, T cell surface glycoprotein CD3 epsilon chain antibody, T-cell surface antigen T3/Leu-4 epsilon chain antibody, T-cell surface glycoprotein CD3 epsilon chain antibody, T3E antibody, TCRE antibody

UniProt

P07766

途径

TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway