SOCS7 抗体 (AA 6-165)
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- 抗原 See all SOCS7 抗体
- SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
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抗原表位
- AA 6-165
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SOCS7 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 人, 大鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Suppressor of cytokine signaling 7 protein (6-165AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
- 别名
- SOCS7 (SOCS7 产品)
- 别名
- NAP4 antibody, NCKAP4 antibody, SOCS4 antibody, SOCS6 antibody, 2310063P06Rik antibody, C85125 antibody, Nap4 antibody, GB13951 antibody, zgc:175115 antibody, SOCS7 antibody, socs7 antibody, suppressor of cytokine signaling 7 antibody, suppressor of cytokine signaling antibody, SOCS7 antibody, Socs7 antibody, LOC413772 antibody, socs7 antibody
- 背景
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Background: Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Aliases: Ash and phospholipase C gamma-binding protein antibody, NAP 4 antibody, NAP 4 Fragment antibody, NAP-4 antibody, NAP4 antibody, Nck antibody, Nck Ash and phospholipase C binding protein antibody, Nck Ash and phospholipase C gamma binding protein antibody, Nck associated protein 4 antibody, Nck-associated protein 4 antibody, NCKAP4 antibody, SH2 domain containing SOCS box protein antibody, SOCS 7 antibody, SOCS-7 antibody, SOCS4 antibody, SOCS6 antibody, Socs7 antibody, SOCS7_HUMAN antibody, Suppressor of cytokine signaling 7 antibody
- UniProt
- O14512
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