SOCS5 抗体 (AA 1-270)
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- 抗原 See all SOCS5 抗体
- SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))
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抗原表位
- AA 1-270
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SOCS5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Suppressor of cytokine signaling 5 protein (1-270AA)
- 亚型
- IgG
- Top Product
- Discover our top product SOCS5 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))
- 别名
- SOCS5 (SOCS5 产品)
- 别名
- SOCS5 antibody, cis6 antibody, cish5 antibody, cish6 antibody, socs-5 antibody, GB18949 antibody, socs5 antibody, zgc:153506 antibody, CIS6 antibody, CISH6 antibody, Cish5 antibody, SOCS-5 antibody, 1810018L08Rik antibody, mKIAA0671 antibody, RGD1564914 antibody, suppressor of cytokine signaling 5 antibody, suppressor of cytokine signaling 5a antibody, suppressor of cytokine signaling 5 L homeolog antibody, SOCS5 antibody, socs5 antibody, LOC552036 antibody, socs5a antibody, Tsp_07018 antibody, socs5.L antibody, Socs5 antibody
- 背景
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Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits for instance EGF signaling by mediating the degradation of the EGF receptor/EGFR. Involved in the regulation of T-helper cell differentiation by inhibiting of the IL4 signaling pathway which promotes differentiation into the Th2 phenotype. Can also partially inhibit IL6 and LIF signaling.
Aliases: SOCS5 antibody, CIS6 antibody, CISH5 antibody, CISH6 antibody, KIAA0671Suppressor of cytokine signaling 5 antibody, SOCS-5 antibody, Cytokine-inducible SH2 protein 6 antibody, CIS-6 antibody, Cytokine-inducible SH2-containing protein 5 antibody
- UniProt
- O75159
- 途径
- JAK/STAT Signaling, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process
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