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- 抗原 See all SMC5 抗体
- SMC5 (Structural Maintenance of Chromosomes 5 (SMC5))
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抗原表位
- AA 296-403
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMC5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Structural maintenance of chromosomes protein 5 protein (296-403AA)
- 亚型
- IgG
- Top Product
- Discover our top product SMC5 Primary Antibody
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anti-Structural Maintenance of Chromosomes 5 (SMC5) (Internal Region) antibody
Verified SMC5 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 5 (SMC5) (AA 872-1101) antibodySMC5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 5 (SMC5) (AA 992-1101) antibodySMC5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SMC5 (Structural Maintenance of Chromosomes 5 (SMC5))
- 别名
- SMC5 (SMC5 产品)
- 别名
- F1N13.60 antibody, F1N13_60 antibody, structural maintenance of chromosomes 5 antibody, SMC-5 antibody, SMC5L1 antibody, MLZ-453 antibody, Smc5l1 antibody, mKIAA0594 antibody, mSMC5 antibody, structural maintenance of chromosomes 5 antibody, structural maintenance of chromosomes 5 S homeolog antibody, SMC5 antibody, smc5 antibody, Smc5 antibody, smc5.S antibody
- 背景
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Background: Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression, the function seems to be independent of SMC6. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome (PubMed:26983541).
Aliases: SMC5 antibody, KIAA0594 antibody, SMC5L1 antibody, Structural maintenance of chromosomes protein 5 antibody, SMC protein 5 antibody, SMC-5 antibody, hSMC5 antibody
- UniProt
- Q8IY18
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