SART3 抗体 (AA 600-900)
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- 抗原 See all SART3 抗体
- SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))
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抗原表位
- AA 600-900
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SART3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Squamous cell carcinoma antigen recognized by T-cells 3 protein (600-900AA)
- 亚型
- IgG
- Top Product
- Discover our top product SART3 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))
- 别名
- SART3 (SART3 产品)
- 别名
- SART3 antibody, DKFZp469J2418 antibody, si:ch211-191d15.4 antibody, wu:fc51h03 antibody, DSAP1 antibody, P100 antibody, RP11-13G14 antibody, TIP110 antibody, p110 antibody, p110(nrb) antibody, AU045857 antibody, mKIAA0156 antibody, squamous cell carcinoma antigen recognized by T-cells 3 antibody, squamous cell carcinoma antigen recognized by T-cells 3 L homeolog antibody, squamous cell carcinoma antigen recognized by T cells 3 antibody, SART3 antibody, sart3 antibody, sart3.L antibody, Sart3 antibody
- 背景
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Background: U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation (PubMed:12032085). Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites (PubMed:14749385). May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly (PubMed:20595234). May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair (PubMed:24526689). May play a role in hematopoiesis probably through transcription regulation of specific genes including MYC (By similarity).
Aliases: DSAP1 antibody, hSART 3 antibody, hSART-3 antibody, P100 antibody, P110 antibody, p110(nrb) antibody, RP11 13G14 antibody, SART 3 antibody, SART-3 antibody, SART3 antibody, SART3_HUMAN antibody, Squamous cell carcinoma antigen recognized by T cells 3 antibody, Squamous cell carcinoma antigen recognized by T-cells 3 antibody, Tat interacting protein of 110 kDa antibody, Tat-interacting protein of 110 kDa antibody, Tip110 antibody
- UniProt
- Q15020
- 途径
- Ribonucleoprotein Complex Subunit Organization
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