U2AF2 抗体 (AA 124-246)
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- 抗原 See all U2AF2 (U2AF59) 抗体
- U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
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抗原表位
- AA 124-246
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This U2AF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Splicing factor U2AF 65 kDa subunit protein (124-246AA)
- 亚型
- IgG
- Top Product
- Discover our top product U2AF59 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:5000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
- 别名
- U2AF2 (U2AF59 产品)
- 别名
- U2AF65 antibody, 65kDa antibody, u2af65 antibody, U2AF2 antibody, DDBDRAFT_0186947 antibody, DDBDRAFT_0233353 antibody, DDB_0186947 antibody, DDB_0233353 antibody, zgc:110115 antibody, U2 small nuclear RNA auxiliary factor 2 antibody, U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 antibody, U2 small nuclear RNA auxiliary factor 2 S homeolog antibody, RNA recognition motif-containing protein RRM antibody, Splicing factor U2AF 65 kDa subunit antibody, U2 small nuclear RNA auxiliary factor 2a antibody, U2AF2 antibody, U2af2 antibody, u2af2.S antibody, u2af2 antibody, u2af2a antibody
- 背景
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Background: Necessary for the splicing of pre-mRNA. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing (PubMed:21536736). Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10.
Aliases: hU2AF(65) antibody, hU2AF65 antibody, Splicing factor U2AF 65 kDa subunit antibody, U2 (RNU2) small nuclear RNA auxiliary factor 2 antibody, U2 auxiliary factor 65 kDa subunit antibody, U2 small nuclear ribonucleoprotein auxiliary factor (65kD) antibody, U2 small nuclear RNA auxiliary factor 2 antibody, U2 snRNP auxiliary factor large subunit antibody, U2af2 antibody, U2AF2_HUMAN antibody, U2AF65 antibody
- UniProt
- P26368
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