SKA3 抗体 (AA 101-195)
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- 抗原 See all SKA3 抗体
- SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))
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抗原表位
- AA 101-195
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SKA3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Spindle and kinetochore-associated protein 3 protein (101-195AA)
- 亚型
- IgG
- Top Product
- Discover our top product SKA3 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))
- 别名
- SKA3 (SKA3 产品)
- 别名
- C13orf3 antibody, RAMA1 antibody, RGD1307201 antibody, C12H13ORF3 antibody, fc23d11 antibody, si:rp71-68n21.13 antibody, wu:fc23d11 antibody, rama1 antibody, F630043A04Rik antibody, spindle and kinetochore associated complex subunit 3 antibody, spindle and kinetochore associated complex subunit 3 L homeolog antibody, SKA3 antibody, Ska3 antibody, ska3 antibody, ska3.L antibody
- 背景
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Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:19289083, PubMed:19360002, PubMed:23085020). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083, PubMed:19360002). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083). In the complex, it mediates the microtubule-stimulated oligomerization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).
Aliases: C13orf3 antibody, RAMA1 antibody, SKA3 antibody, SKA3_HUMAN antibody, Spindle and kinetochore associated complex subunit 3 antibody, Spindle and kinetochore-associated protein 3 antibody
- UniProt
- Q8IX90
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