SPAG5 抗体 (AA 1-300)
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- 抗原 See all SPAG5 抗体
- SPAG5 (Sperm Associated Antigen 5 (SPAG5))
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抗原表位
- AA 1-300
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPAG5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Sperm-associated antigen 5 protein (1-300AA)
- 亚型
- IgG
- Top Product
- Discover our top product SPAG5 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SPAG5 (Sperm Associated Antigen 5 (SPAG5))
- 别名
- SPAG5 (SPAG5 产品)
- 别名
- SPAG5 antibody, DEEPEST antibody, MAP126 antibody, hMAP126 antibody, AI874642 antibody, D11Bhm180e antibody, Deepest antibody, Mastrin antibody, S17 antibody, sperm associated antigen 5 antibody, sperm-associated antigen 5 antibody, SPAG5 antibody, LOC739263 antibody, Spag5 antibody
- 背景
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Background: Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. In complex with SKAP, promotes stable microtubule-kinetochore attachments. May contribute to the regulation of separase activity. May regulate AURKA localization to mitotic spindle, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes. In non-mitotic cells, upon stress induction, inhibits mammalian target of rapamycin complex 1 (mTORC1) association and recruits the mTORC1 component RPTOR to stress granules (SGs), thereby preventing mTORC1 hyperactivation-induced apoptosis. May enhance GSK3B-mediated phosphorylation of other substrates, such as MAPT/TAU.
Aliases: Astrin antibody, Deepest antibody, hMAP 126 antibody, hMAP126 antibody, MAP 126 antibody, MAP126 antibody, Mitotic spindle associated protein antibody, Mitotic spindle associated protein p126 antibody, Mitotic spindle coiled coil related protein antibody, Mitotic spindle-associated protein p126 antibody, SPAG 5 antibody, SPAG5 antibody, SPAG5_HUMAN antibody, Sperm associated antigen 5 antibody, Sperm tail protein Spag 5 antibody, Sperm tail protein Spag5 antibody, Sperm-associated antigen 5 antibody
- UniProt
- Q96R06
- 途径
- M Phase
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