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SNX5 抗体 (AA 7-245)

SNX5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7170398
发货至: 中国
  • 抗原 See all SNX5 抗体
    SNX5 (Sorting Nexin 5 (SNX5))
    抗原表位
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 7-245
    适用
    • 40
    • 14
    • 12
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 38
    • 2
    克隆类型
    • 40
    多克隆
    标记
    • 15
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SNX5 antibody is un-conjugated
    应用范围
    • 29
    • 13
    • 13
    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Sorting nexin-5 protein (7-245AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:500-1:1000, IF:1:200-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SNX5 (Sorting Nexin 5 (SNX5))
    别名
    SNX5 (SNX5 产品)
    别名
    0910001N05Rik antibody, 1810032P22Rik antibody, AU019504 antibody, D2Ertd52e antibody, id:ibd5091 antibody, wu:fa66c10 antibody, wu:fi28h04 antibody, zgc:55769 antibody, SNX5 antibody, snx5 antibody, sorting nexin 5 antibody, sorting nexin 5 S homeolog antibody, SNX5 antibody, Snx5 antibody, snx5.S antibody, snx5 antibody
    背景

    Background: Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) (PubMed:15561769). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Does not have in vitro vesicle-to-membrane remodeling activity (PubMed:23085988). Involved in retrograde transport of lysosomal enzyme receptor IGF2R (PubMed:17148574, PubMed:18596235). May function as link between endosomal transport vesicles and dynactin (Probable). Plays a role in the internalization of EGFR after EGF stimulation (Probable). Involved in EGFR endosomal sorting and degradation, the function involves PIP5K1C isoform 3 and is retromer-independent (PubMed:23602387). Together with PIP5K1C isoform 3 facilitates HGS interaction with ubiquitinated EGFR, which initiates EGFR sorting to intraluminal vesicles (ILVs) of the multivesicular body for subsequent lysosomal degradation (Probable). Involved in E-cadherin sorting and degradation, inhibits PIP5K1C isoform 3-mediated E-cadherin degradation (PubMed:24610942). Plays a role in macropinocytosis (PubMed:18854019, PubMed:21048941).

    Aliases: 0910001N05Rik antibody, 1810032P22Rik antibody, AU019504 antibody, D2Ertd52e antibody, FLJ10931 antibody, OTTHUMP00000030340 antibody, OTTHUMP00000062927 antibody, OTTMUSP00000003367 antibody, OTTMUSP00000003368 antibody, RP11-504H3.2 antibody, RP23-35E16.2 antibody, snoRNA MBI-43 antibody, SNX 5 antibody, SNX5 antibody, SNX5_HUMAN antibody, Sorting nexin 5 antibody, Sorting nexin-5 antibody

    UniProt
    Q9Y5X3
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