SLC38A9 抗体 (AA 1-119) (HRP)
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- 抗原 See all SLC38A9 抗体
- SLC38A9 (Solute Carrier Family 38, Member 9 (SLC38A9))
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抗原表位
- AA 1-119
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLC38A9 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Sodium-coupled neutral amino acid transporter 9 protein (1-119AA)
- 亚型
- IgG
- Top Product
- Discover our top product SLC38A9 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SLC38A9 (Solute Carrier Family 38, Member 9 (SLC38A9))
- 别名
- SLC38A9 (SLC38A9 产品)
- 别名
- MGC81406 antibody, 4833412L08Rik antibody, 6720411P22Rik antibody, 9130023D20Rik antibody, 9430067K09Rik antibody, A730092C09 antibody, RGD1311881 antibody, solute carrier family 38 member 9 antibody, solute carrier family 38 member 9 L homeolog antibody, solute carrier family 38, member 9 antibody, SLC38A9 antibody, slc38a9.L antibody, slc38a9 antibody, Slc38a9 antibody
- 背景
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Background: Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids (PubMed:25561175, PubMed:25567906). Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids, suggesting that it acts as an amino acid sensor instead (PubMed:25561175, PubMed:25567906). The high concentration of arginine in lysosomes suggests that it acts as an arginine sensor (PubMed:25567906).
Aliases: FLJ46104 antibody, FLJ90709 antibody, Homo sapiens solute carrier family 38, member 9 antibody, MGC120544 antibody, OTTHUMP00000161835 antibody, Putative sodium coupled neutral amino acid transporter 9 antibody, Putative sodium-coupled neutral amino acid transporter 9 antibody, Putative uncharacterized protein FLJ90709 antibody, S38A9_HUMAN antibody, SLC38A9 antibody
- UniProt
- Q8NBW4
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