STAT2 抗体 (AA 571-851)
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- 抗原 See all STAT2 抗体
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
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抗原表位
- AA 571-851
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STAT2 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Signal transducer and activator of transcription 2 protein (571-851AA)
- 亚型
- IgG
- Top Product
- Discover our top product STAT2 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
- 别名
- STAT2 (STAT2 产品)
- 别名
- wu:fj84d07 antibody, p113 antibody, stat2 antibody, 1600010G07Rik antibody, AW496480 antibody, ISGF-3 antibody, P113 antibody, STAT113 antibody, signal transducer and activator of transcription 2 antibody, AGAP000099-PA antibody, stat2 antibody, STAT2 antibody, Stat2 antibody
- 背景
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Background: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Aliases: Homo sapiens interferon alpha induced transcriptional activator antibody, interferon alpha induced transcriptional activator antibody, ISGF 3 antibody, ISGF3 antibody, MGC59816 antibody, P113 antibody, signal transducer and activator of transcription 2 113kD antibody, Signal transducer and activator of transcription 2 antibody, STAT113 antibody, Stat2 antibody, STAT2_HUMAN antibody
- UniProt
- P52630
- 途径
- JAK/STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
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