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SPPL2B 抗体 (AA 492-592) (HRP)

SPPL2B 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7169630
发货至: 中国
  • 抗原 See all SPPL2B 抗体
    SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))
    抗原表位
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 492-592
    适用
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 11
    克隆类型
    • 11
    多克隆
    标记
    • 9
    • 1
    • 1
    This SPPL2B antibody is conjugated to HRP
    应用范围
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Signal peptide peptidase-like 2B protein (492-592AA)
    亚型
    IgG
    Top Product
    Discover our top product SPPL2B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))
    别名
    SPPL2B (SPPL2B 产品)
    别名
    SPPL2B antibody, wu:fc16e01 antibody, wu:fc85d12 antibody, zgc:136525 antibody, MGC147524 antibody, IMP-4 antibody, IMP4 antibody, PSH4 antibody, PSL1 antibody, 3110056O03Rik antibody, AW550292 antibody, RGD1308556 antibody, signal peptide peptidase-like 2 antibody, signal peptide peptidase like 2B antibody, signal peptide peptidase like 2B S homeolog antibody, signal peptide peptidase-like 2B antibody, sppl2 antibody, sppl2b antibody, sppl2b.S antibody, SPPL2B antibody, Sppl2b antibody
    背景

    Background: Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing (PubMed:16829952, PubMed:16829951, PubMed:17965014, PubMed:19114711, PubMed:22194595). Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus (PubMed:16829952, PubMed:16829951). May play a role in the regulation of innate and adaptive immunity (PubMed:16829952). Catalyzes the intramembrane cleavage of the simian foamy virus processed leader peptide gp18 of the envelope glycoprotein gp130 dependently of prior ectodomain shedding by furin or furin-like proprotein convertase (PC)-mediated cleavage proteolysis (PubMed:23132852).

    Aliases: SPPL2B antibody, IMP4 antibody, KIAA1532 antibody, PSL1 antibody, Signal peptide peptidase-like 2B antibody, SPP-like 2B antibody, SPPL2b antibody, EC 3.4.23.- antibody, Intramembrane protease 4 antibody, IMP-4 antibody, Presenilin homologous protein 4 antibody, PSH4 antibody, Presenilin-like protein 1 antibody

    UniProt
    Q8TCT7
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