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- 抗原 See all SPPL2B 抗体
- SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))
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抗原表位
- AA 492-592
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPPL2B antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Signal peptide peptidase-like 2B protein (492-592AA)
- 亚型
- IgG
- Top Product
- Discover our top product SPPL2B Primary Antibody
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anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (N-Term) antibody
SPPL2B 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (N-Term) antibodySPPL2B 适用: 人, 大鼠, Cow, 马, 小鼠, Pig, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 93-142) antibodySPPL2B 适用: 人, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 196-229) antibodySPPL2B 适用: 人 WB 宿主: 兔 Polyclonal RB53139 unconjugated
anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 126-160) antibodySPPL2B 适用: 人 WB 宿主: 兔 Polyclonal RB53138 unconjugated
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- 应用备注
- Recommended dilution: IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))
- 别名
- SPPL2B (SPPL2B 产品)
- 别名
- SPPL2B antibody, wu:fc16e01 antibody, wu:fc85d12 antibody, zgc:136525 antibody, MGC147524 antibody, IMP-4 antibody, IMP4 antibody, PSH4 antibody, PSL1 antibody, 3110056O03Rik antibody, AW550292 antibody, RGD1308556 antibody, signal peptide peptidase-like 2 antibody, signal peptide peptidase like 2B antibody, signal peptide peptidase like 2B S homeolog antibody, signal peptide peptidase-like 2B antibody, sppl2 antibody, sppl2b antibody, sppl2b.S antibody, SPPL2B antibody, Sppl2b antibody
- 背景
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Background: Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing (PubMed:16829952, PubMed:16829951, PubMed:17965014, PubMed:19114711, PubMed:22194595). Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus (PubMed:16829952, PubMed:16829951). May play a role in the regulation of innate and adaptive immunity (PubMed:16829952). Catalyzes the intramembrane cleavage of the simian foamy virus processed leader peptide gp18 of the envelope glycoprotein gp130 dependently of prior ectodomain shedding by furin or furin-like proprotein convertase (PC)-mediated cleavage proteolysis (PubMed:23132852).
Aliases: SPPL2B antibody, IMP4 antibody, KIAA1532 antibody, PSL1 antibody, Signal peptide peptidase-like 2B antibody, SPP-like 2B antibody, SPPL2b antibody, EC 3.4.23.- antibody, Intramembrane protease 4 antibody, IMP-4 antibody, Presenilin homologous protein 4 antibody, PSH4 antibody, Presenilin-like protein 1 antibody
- UniProt
- Q8TCT7
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