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SPPL2A 抗体 (AA 26-172) (HRP)

SPPL2A 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7169626
发货至: 中国
  • 抗原 See all SPPL2A 抗体
    SPPL2A (Signal Peptide Peptidase-Like 2A (SPPL2A))
    抗原表位
    • 7
    • 4
    • 2
    • 2
    • 1
    AA 26-172
    适用
    • 16
    • 1
    • 1
    宿主
    • 14
    • 2
    克隆类型
    • 15
    • 1
    多克隆
    标记
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    This SPPL2A antibody is conjugated to HRP
    应用范围
    • 13
    • 13
    • 10
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Signal peptide peptidase-like 2A protein (26-172AA)
    亚型
    IgG
    Top Product
    Discover our top product SPPL2A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SPPL2A (Signal Peptide Peptidase-Like 2A (SPPL2A))
    别名
    SPPL2A (SPPL2A 产品)
    别名
    RGD1563001 antibody, SPPL2A antibody, LOC453430 antibody, LOC100231183 antibody, IMP3 antibody, PSL2 antibody, 2010106G01Rik antibody, C130089K23Rik antibody, signal peptide peptidase-like 2A antibody, signal peptide peptidase like 2A antibody, Signal peptide peptidase-like 2A antibody, Sppl2a antibody, SPPL2A antibody, sppl2a antibody, psl2 antibody
    背景

    Background: Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in FASLG, ITM2B and TNF processing (PubMed:16829952, PubMed:16829951, PubMed:17557115, PubMed:17965014). Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus (PubMed:16829952). Also responsible for the intramembrane cleavage of Fas antigen ligand FASLG, which promotes the release of the intracellular FasL domain (FasL ICD) (PubMed:17557115). May play a role in the regulation of innate and adaptive immunity (PubMed:16829952). Catalyzes the intramembrane cleavage of the simian foamy virus envelope glycoprotein gp130 independently of prior ectodomain shedding by furin or furin-like proprotein convertase (PC)-mediated cleavage proteolysis (PubMed:23132852).

    Aliases: SPPL2A antibody, IMP3 antibody, PSL2 antibody, PSEC0147 antibody, Signal peptide peptidase-like 2A antibody, SPP-like 2A antibody, SPPL2a antibody, EC 3.4.23.- antibody, Intramembrane protease 3 antibody, IMP-3 antibody, Presenilin-like protein 2 antibody

    UniProt
    Q8TCT8
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