Shugoshin 抗体 (AA 260-439) (HRP)
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- 抗原 See all Shugoshin (SGOL1) 抗体
- Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
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抗原表位
- AA 260-439
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Shugoshin antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Shugoshin 1 protein (260-439AA)
- 亚型
- IgG
- Top Product
- Discover our top product SGOL1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
- 别名
- SGO1 (SGOL1 产品)
- 别名
- sgo1 antibody, NY-BR-85 antibody, SGO antibody, Sgo1 antibody, 3300001M08Rik antibody, C81037 antibody, shugoshin 1 antibody, shugoshin centromeric cohesion 1 antibody, shugoshin 1 L homeolog antibody, Sgo1 antibody, sgo1 antibody, sgo1.L antibody, SGO1 antibody
- 背景
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Background: Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the STAG2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by ESPL1/separase at anaphase. Essential for proper chromosome segregation during mitosis and this function requires interaction with PPP2R1A. Its phosphorylated form is necessary for chromosome congression and for the proper attachment of spindle microtubule to the kinetochore. Necessary for kinetochore localization of PLK1 and CENPF. May play a role in the tension sensing mechanism of the spindle-assembly checkpoint by regulating PLK1 kinetochore affinity. Isoform 3 plays a role in maintaining centriole cohesion involved in controlling spindle pole integrity.
Aliases: hSgo 1 antibody, hSgo1 antibody, NY BR 85 antibody, Serologically defined breast cancer antigen NY BR 85 antibody, Serologically defined breast cancer antigen NY-BR-85 antibody, SGO 1 antibody, SGO antibody, SGO L1 antibody, SGO1 antibody, SGOL 1 antibody, SGOL1 antibody, SGOL1_HUMAN antibody, Shugoshin 1AB protein antibody, Shugoshin 1CD protein antibody, Shugoshin 1EFprotein antibody, Shugoshin 1GH protein antibody, Shugoshin 1KL protein antibody, Shugoshin like 1 (S. pombe) antibody, Shugoshin like 1 antibody, Shugoshin-like 1 antibody
- UniProt
- Q5FBB7
- 途径
- Maintenance of Protein Location
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