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Shugoshin 抗体 (AA 260-439) (Biotin)

SGOL1 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7169546
发货至: 中国
  • 抗原 See all Shugoshin (SGOL1) 抗体
    Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
    抗原表位
    • 10
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 260-439
    适用
    • 44
    • 5
    • 5
    • 1
    • 1
    宿主
    • 42
    • 3
    克隆类型
    • 43
    • 2
    多克隆
    标记
    • 25
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Shugoshin antibody is conjugated to Biotin
    应用范围
    • 31
    • 26
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Shugoshin 1 protein (260-439AA)
    亚型
    IgG
    Top Product
    Discover our top product SGOL1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
    别名
    SGO1 (SGOL1 产品)
    别名
    sgo1 antibody, NY-BR-85 antibody, SGO antibody, Sgo1 antibody, 3300001M08Rik antibody, C81037 antibody, shugoshin 1 antibody, shugoshin centromeric cohesion 1 antibody, shugoshin 1 L homeolog antibody, Sgo1 antibody, sgo1 antibody, sgo1.L antibody, SGO1 antibody
    背景

    Background: Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the STAG2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by ESPL1/separase at anaphase. Essential for proper chromosome segregation during mitosis and this function requires interaction with PPP2R1A. Its phosphorylated form is necessary for chromosome congression and for the proper attachment of spindle microtubule to the kinetochore. Necessary for kinetochore localization of PLK1 and CENPF. May play a role in the tension sensing mechanism of the spindle-assembly checkpoint by regulating PLK1 kinetochore affinity. Isoform 3 plays a role in maintaining centriole cohesion involved in controlling spindle pole integrity.

    Aliases: hSgo 1 antibody, hSgo1 antibody, NY BR 85 antibody, Serologically defined breast cancer antigen NY BR 85 antibody, Serologically defined breast cancer antigen NY-BR-85 antibody, SGO 1 antibody, SGO antibody, SGO L1 antibody, SGO1 antibody, SGOL 1 antibody, SGOL1 antibody, SGOL1_HUMAN antibody, Shugoshin 1AB protein antibody, Shugoshin 1CD protein antibody, Shugoshin 1EFprotein antibody, Shugoshin 1GH protein antibody, Shugoshin 1KL protein antibody, Shugoshin like 1 (S. pombe) antibody, Shugoshin like 1 antibody, Shugoshin-like 1 antibody

    UniProt
    Q5FBB7
    途径
    Maintenance of Protein Location
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