PPP1CC 抗体 (Catalytic Subunit)
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- 抗原 See all PPP1CC 抗体
- PPP1CC (Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC))
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抗原表位
- AA 151-323, Catalytic Subunit
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPP1CC antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Serine/threonine-protein phosphatase PP1-gamma catalytic subunit protein (151-323AA)
- 亚型
- IgG
- Top Product
- Discover our top product PPP1CC Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PPP1CC (Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC))
- 别名
- PPP1CC (PPP1CC 产品)
- 别名
- PP-1G antibody, ppp1g antibody, PP1 antibody, dis2m1 antibody, fe06g11 antibody, fi22e08 antibody, wu:fe06g11 antibody, wu:fi22e08 antibody, PP1C antibody, PPP1G antibody, Ppp1cc1 antibody, ppp1cc-a antibody, protein phosphatase 1, catalytic subunit, gamma isozyme antibody, protein phosphatase 1, catalytic subunit, gamma isoform antibody, protein phosphatase 1 catalytic subunit gamma antibody, protein phosphatase 1, catalytic subunit, gamma isozyme L homeolog antibody, ppp1cc antibody, Ppp1cc antibody, PPP1CC antibody, ppp1cc.L antibody
- 背景
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Background: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the \\\'Ser-418\\\' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).
Aliases: PP 1G antibody, PP-1G antibody, PP1C antibody, PP1G antibody, PP1G_HUMAN antibody, PP1gamma antibody, PPP 1G antibody, PPP1CC antibody, PPP1G antibody, Protein phosphatase 1, catalytic subunit, gamma isozyme antibody, Protein phosphatase 1C catalytic subunit antibody, Serine/threonine phosphatase 1 gamma antibody, Serine/threonine protein phosphatase PP1 gamma catalytic subunit antibody, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit antibody
- UniProt
- P36873
- 途径
- Cellular Glucan Metabolic Process, Lipid Metabolism
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