WNK3 抗体 (AA 1018-1181)
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- 抗原 See all WNK3 抗体
- WNK3 (WNK Lysine Deficient Protein Kinase 3 (WNK3))
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抗原表位
- AA 1018-1181
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WNK3 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Serine/threonine-protein kinase WNK3 protein (1018-1181AA)
- 亚型
- IgG
- Top Product
- Discover our top product WNK3 Primary Antibody
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- 应用备注
- Recommended dilution: IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- WNK3 (WNK Lysine Deficient Protein Kinase 3 (WNK3))
- 别名
- WNK3 (WNK3 产品)
- 别名
- fc63h12 antibody, PRKWNK3 antibody, Prkwnk3 antibody, Wnk3-ps antibody, RGD1563131 antibody, wu:fc63h12 antibody, WNK lysine deficient protein kinase 3 antibody, wu:fc63h12 antibody, LOC100363278 antibody, WNK3 antibody, Wnk3 antibody
- 背景
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Background: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively (PubMed:16275913, PubMed:16275911, PubMed:16357011). Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway (PubMed:18768590). Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner.
Aliases: KIAA1566 antibody, PRKWNK 3 antibody, PRKWNK3 antibody, Protein kinase lysine deficient 3 antibody, Protein kinase lysine-deficient 3 antibody, Protein kinase with no lysine 3 antibody, Serine/threonine protein kinase WNK3 antibody, Serine/threonine-protein kinase WNK3 antibody, WNK 3 antibody, WNK lysine deficient protein kinase 3 antibody, Wnk3 antibody, WNK3_HUMAN antibody
- UniProt
- Q9BYP7
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