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WNK3 抗体 (AA 1018-1181)

WNK3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7169230
发货至: 中国
  • 抗原 See all WNK3 抗体
    WNK3 (WNK Lysine Deficient Protein Kinase 3 (WNK3))
    抗原表位
    • 15
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1018-1181
    适用
    • 54
    • 25
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 52
    • 3
    克隆类型
    • 53
    • 2
    多克隆
    标记
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WNK3 antibody is un-conjugated
    应用范围
    • 27
    • 21
    • 14
    • 13
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Serine/threonine-protein kinase WNK3 protein (1018-1181AA)
    亚型
    IgG
    Top Product
    Discover our top product WNK3 Primary Antibody
  • 应用备注
    Recommended dilution: IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    WNK3 (WNK Lysine Deficient Protein Kinase 3 (WNK3))
    别名
    WNK3 (WNK3 产品)
    别名
    fc63h12 antibody, PRKWNK3 antibody, Prkwnk3 antibody, Wnk3-ps antibody, RGD1563131 antibody, wu:fc63h12 antibody, WNK lysine deficient protein kinase 3 antibody, wu:fc63h12 antibody, LOC100363278 antibody, WNK3 antibody, Wnk3 antibody
    背景

    Background: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively (PubMed:16275913, PubMed:16275911, PubMed:16357011). Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway (PubMed:18768590). Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner.

    Aliases: KIAA1566 antibody, PRKWNK 3 antibody, PRKWNK3 antibody, Protein kinase lysine deficient 3 antibody, Protein kinase lysine-deficient 3 antibody, Protein kinase with no lysine 3 antibody, Serine/threonine protein kinase WNK3 antibody, Serine/threonine-protein kinase WNK3 antibody, WNK 3 antibody, WNK lysine deficient protein kinase 3 antibody, Wnk3 antibody, WNK3_HUMAN antibody

    UniProt
    Q9BYP7
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