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WNK2 抗体 (AA 1177-1464) (FITC)

WNK2 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7169228
发货至: 中国
  • 抗原 See all WNK2 抗体
    WNK2 (WNK Lysine Deficient Protein Kinase 2 (WNK2))
    抗原表位
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1177-1464
    适用
    • 19
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 17
    • 3
    克隆类型
    • 17
    • 3
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WNK2 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Serine/threonine-protein kinase WNK2 protein (1177-1464AA)
    亚型
    IgG
    Top Product
    Discover our top product WNK2 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    WNK2 (WNK Lysine Deficient Protein Kinase 2 (WNK2))
    别名
    WNK2 (WNK2 产品)
    别名
    WNK2 antibody, ARABIDOPSIS THALIANA WITH NO K 2 antibody, ATWNK2 antibody, PROTEIN KINASE antibody, ZIK3 antibody, with no lysine (K) kinase 2 antibody, NY-CO-43 antibody, P/OKcl.13 antibody, PRKWNK2 antibody, SDCCAG43 antibody, 1810073P09Rik antibody, AW122246 antibody, ESTM15 antibody, X83337 antibody, mKIAA1760 antibody, RGD1307284 antibody, WNK lysine deficient protein kinase 2 antibody, with no lysine (K) kinase 2 antibody, WNK2 antibody, Wnk2 antibody
    背景

    Background: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SLC12A2, SCNN1A, SCNN1B, SCNN1D and SGK1 and inhibits SLC12A5. Negatively regulates the EGF-induced activation of the ERK/MAPK-pathway and the downstream cell cycle progression. Affects MAPK3/MAPK1 activity by modulating the activity of MAP2K1 and this modulation depends on phosphorylation of MAP2K1 by PAK1. WNK2 acts by interfering with the activity of PAK1 by controlling the balance of the activity of upstream regulators of PAK1 activity, RHOA and RAC1, which display reciprocal activity.

    Aliases: WNK2 antibody, KIAA1760 antibody, PRKWNK2 antibody, SDCCAG43 antibody, P/OKcl.13 antibody, Serine/threonine-protein kinase WNK2 antibody, EC 2.7.11.1 antibody, Antigen NY-CO-43 antibody, Protein kinase lysine-deficient 2 antibody, Protein kinase with no lysine 2 antibody, Serologically defined colon cancer antigen 43 antibody

    UniProt
    Q9Y3S1
    途径
    Photoperiodism
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