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WNK1 抗体 (AA 1-207) (FITC)

WNK1 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7169224
发货至: 中国
  • 抗原 See all WNK1 抗体
    WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))
    抗原表位
    • 15
    • 12
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-207
    适用
    • 68
    • 43
    • 40
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 83
    克隆类型
    • 74
    • 9
    多克隆
    标记
    • 33
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WNK1 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Serine/threonine-protein kinase WNK1 protein (1-207AA)
    亚型
    IgG
    Top Product
    Discover our top product WNK1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))
    别名
    WNK1 (WNK1 产品)
    背景

    Background: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L. Acts as a scaffold to inhibit SLC4A4, SLC26A6 as well as CFTR activities and surface expression, recruits STK39 which mediates the inhibition (By similarity).

    Aliases: Erythrocyte 65 kDa protein antibody, HSAN2 antibody, HSN2 antibody, hWNK1 antibody, KDP antibody, KIAA0344 antibody, Kinase deficient protein antibody, MGC163339 antibody, MGC163341 antibody, p65 antibody, PPP1R167 antibody, PRKWNK1 antibody, Prostate derived sterile 20 like kinase antibody, Protein kinase lysine deficient 1 antibody, Protein kinase lysine-deficient 1 antibody, Protein kinase with no lysine 1 antibody, Protein phosphatase 1, regulatory subunit 167 antibody, PSK antibody, Serine/threonine protein kinase WNK1 1 antibody, Serine/threonine protein kinase WNK1 2 antibody, Serine/threonine protein kinase WNK1 antibody, Serine/threonine-protein kinase WNK1 antibody, With no K antibody, WNK lysine deficient protein kinase 1 antibody, WNK lysine deficient protein kinase 1 isoform antibody, WNK1 antibody, WNK1_HUMAN antibody

    UniProt
    Q9H4A3
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